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課程名稱 |
有機金屬化學
Organometallic Chemistry |
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開課學期 |
102-1 |
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授課對象 |
理學院 化學所化學生物學組 |
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授課教師 |
小宮三四郎 |
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課號 |
Chem5017 |
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課程識別碼 |
223 U0550 |
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班次 |
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學分 |
2 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期二5,6(12:20~14:10) |
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上課地點 |
化210室 |
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備註 |
本課程中文授課,使用英文教科書。外系所學生欲選修，須經授課老師同意。與客座教授合開。與劉緒宗合開
限學士班三年級以上 且 限本系所學生(含輔系、雙修生)
總人數上限：30人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1021OM33661661 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
Organometallic chemistry develops enormously in recent 60 years, because its wide range of important and useful applications in organic syntheses and catalyses. It also introduced many new fundamental concepts in chemistry. Lecture includes fundamental concepts of organotransition metal chemistry and their applications to organic syntheses and homogeneous catalyses. Only representative organic reactions will be employed here, since it is impossible to introduce huge accomplishments in this area.
來自日本的 小宮三四郎教授 會參與教學 |
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課程目標 |
1.Fundamental concept of Organometallic compounds
2.Fundamental reactions: Oxidative addition, reductive elimination, migratory insertion, beta-elimination.
3.Metal-carbon bonds: M-C, M=C and M≡C
4.Metal-C=C Pi-Bond
5.Homogeneous and heterogeneous catalyses
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課程要求 |
To understand the chemistry on tansition metal ions
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預期每週課後學習時數 |
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Office Hours |
另約時間 備註： by appointment |
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指定閱讀 |
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參考書目 |
1.有機金屬化學(日文) 小宮三四郎、碇屋隆雄著
2. Organotransition Metal Chemistry Akio Yamamoto Wiley
3. Syntheisi of organometallic compounds S. Komiya Wiley
4. Organotranisiton metal chemistry "from bonding to catalysis" J. Hartwig,
UNiversity Science Books.2010. |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/10 |
Introduction (video) and small quiz |
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第2週 |
9/17 |
Chemical Bonding 1 (Basic Concepts including covalent, ionic and coordination bonds, MO theory and VB theory) |
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第3週 |
9/24 |
Chemical Bonding 2 (Crystal Field Theory, Ligand Field Theory using MO theory |
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第5週 |
10/08 |
18-electron rule; Fluxionality of the transition metal complexes |
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第6週 |
10/15 |
General synthesis, property, and structure of organometallic compounds. Acidity of hydrides |
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第7週 |
10/22 |
Naming of organotransition metal complexes
Fundamental reactions of organotransition metal complex: Introduction |
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第8週 |
10/29 |
Dissociation and association (coordination): steric and electronic effects, alkene coordination, mechanisms, stereochemistry |
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第10週 |
11/12 |
Insertion and elimination (insertion of CO, alkene, alkyne, diene, others,beta-elimination |
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第11週 |
11/19 |
Reactions of coordinated ligands (olefin and carbonyl ligands)
Comparison of reactivities between transition and non-transition metal complexes |
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第12週 |
11/26 |
Experimental handling technique of air-sensitive compounds: Max-Plank Schlenk technique and US double manifold-vacuum/nitrogen line with glove-box |
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第13週 |
12/03 |
Homogeneous and heterogeneous catalyses: introduction
Catalyses of alkenes, alkynes and dienes |
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第14週 |
12/10 |
Industrial reactions using carbon monoxide
Development of acetic acid synthesis: role of homogeneous transition metal catalysis). Thermolysis of woods, Hg-assisted synthesis, Wacker process, Monsanto process |
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第15週 |
12/17 |
Organic syntheses using transition metal complexes
Cross coupling reaction |
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第16週 |
12/24 |
P-allyl chemistry; Mizoroki-Heck reaction
Reactions of transition metal carbene complex |
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第17週 |
12/31 |
Asymmtetric reactions and other reactions |
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